After reaching the Majors in August, third baseman Kyle Karros followed it up in an impressive Spring Training to earn an Opening Day roster spot with the Colorado Rockies. The 2021 Greeneville Flyboy got a hit on Opening Day and followed that up with a steal in both the second and third game of the year.

Thirty Appalachian League alumni were selected for Major League Baseball’s third annual edition of Spring Breakout, which took place March 19-22. Spring Breakout serves as a showcase of baseball’s future stars with each Major League Club fielding a team of prospects from their farm system to play a team of top prospects from another organization in an exhibition game.

Jordan Leasure, the alum of the new Appalachian League to reach the Majors, earned a spot in the White Sox's Opening Day roster for the third straight season. The right-hander posted a 3.92 ERA over 64 1/3 innings in his sophomore season.

Twenty Appalachian League alumni appear on MLB Pipeline’s team Top 30 Prospects lists to begin 2026. Kaelen Culpepper (Bluefield ‘22) is the Appy League’s highest ranked prospect at No. 52 on MLB Pipeline’s new Top 100 Prospects list and No. 2 on the Minnesota Twins Top 30 list.

Former Appy League pitcher Trey Cooper signed a Minor League contract with the Chicago White Sox. Cooper pitched for the Burlington Sock Puppets in 2022 and 2024, making an All-Star appearance in '22.