The Appalachian League had five players selected in the first four rounds on Day 1, with 32 overall alumni selected over the course of the 2026 MLB Draft.
2026 Drafted Players
| Round | Pick | Team | Player | Position | School | Appy League Team | Year |
|---|---|---|---|---|---|---|---|
| 2 | 53 | Arizona Diamondbacks | Carson Kerce | SS | Georgia Tech | Johnson City Doughboys | 2024 |
| 4 | 116 | Arizona Diamondbacks | Josh McDevitt | RHP | Missouri | Tri-State Coal Cats | 2024 |
| 4 | 121 | Houston Astros | Kam Durnin | SS | Missouri | Kingsport Axmen | 2025 |
| 4 | 132 | Los Angeles Dodgers | Russell Sandefer | RHP | Florida | Danville Otterbots | 2024 |
| 4C | 134 | San Diego Padres | Alex Conover | OF | Oklahoma State | Danville Otterbots | 2024-25 |
| 5 | 157 | San Diego Padres | James Guyette | RHP | Kansas State | Danville Otterbots | 2024 |
| 6 | 167 | Washington Nationals | Cooper Allen | RHP | UNC Wilmington | Burlington Sock Puppets | 2024 |
| 7 | 196 | Washington Nationals | Gage Peterson | RHP | Appalachian State | Johnson City Doughboys | 2023 |
| 8 | 231 | Athletics | Aidan Weaver | RHP | Duke | Burlington Sock Puppets | 2024 |
| 8 | 235 | Miami Marlins | Rintaro Sasaki | 1B | Stanford | Greeneville Flyboys | 2024 |
| 9 | 264 | St. Louis Cardinals | Jayden Lobliner | C | San Diego | Bristol/Elizabethton | 2023-25 |
| 9 | 268 | San Francisco Giants | Mike Mancini | 2B | Vanderbilt | Kingsport Axmen | 2023 |
| 10 | 286 | Washington Nationals | Nick Williams | OF | Michigan State | Greeneville Flyboys | 2024 |
| 10 | 295 | Miami Marlins | Zach Peters | RHP | Virginia Commonwealth | Princeton/Bluefield | 2023-24 |
| 11 | 335 | San Diego Padres | Chris McHugh | 1B | North Carolina State | Johnson City Doughboys | 2024 |
| 12 | 359 | Kansas City Royals | Lance Hartley | RHP | College of Central Florida | Burlington Sock Puppets | 2025 |
| 12 | 365 | San Diego Padres | Rob Evans | LHP | Miami (FL) | Burlington Sock Puppets | 2023 |
| 13 | 391 | Houston Astros | Jack Beck | SS | Columbia Central HS (TN) | Burlington Sock Puppets | 2026 |
| 13 | 396 | Detroit Tigers | Jett Johnston | RHP | Auburn | Kingsport/Bristol | 2023-24 |
| 14 | 422 | Cincinnati Reds | Ray Ladd | RHP | Radford | Danville Otterbots | 2023-24 |
| 15 | 434 | Colorado Rockies | Ryan Niedzwiedz | 1B | SIU - Edwardsville | Bluefield Ridge Runners | 2025 |
| 15 | 446 | Arizona Diamondbacks | Andrew Evans | RHP | Southern Illinois | Danville Otterbots | 2025 |
| 16 | 471 | Athletics | Tyler August | RHP | Liberty | Danville Otterbots | 2024 |
| 16 | 482 | Cincinnati Reds | Victor Christal | RHP | Johnson County CC | Bluefield Ridge Runners | 2025 |
| 17 | 500 | Baltimore Orioles | Diego Gutierrez | RHP | San Diego | Danville Otterbots | 2026 |
| 17 | 503 | Tampa Bay Rays | McCarty English | RHP | Southern Mississippi | Danville Otterbots | 2026 |
| 17 | 505 | Miami Marlins | Duke McCarron | RHP | Saint Joseph's | Kingsport Axmen | 2024 |
| 17 | 511 | Houston Astros | Ben Tryon | IF | Dallas Baptist | Kingsport Axmen | 2025 |
| 18 | 526 | Washington Nationals | Avery Ortiz | IF | Oklahoma State | Greeneville Flyboys | 2024 |
| 18 | 538 | San Francisco Giants | Ryder Brooks | LHP | UC - Irvine | Danville Otterbots | 2023 |
| 18 | 552 | Toronto Blue Jays | Jake McCoy | LHP | South Carolina | Pulaski River Turtles | 2023 |
| 20 | 604 | Boston Red Sox | Aiden VanDeHatert | LHP | Dallas Baptist | Greeneville Flyboys | 2026 |
* = Did not sign
2026 Undrafted Free Agents
| MLB Team | Player | Position | School | Appy Team | Year |
|---|---|---|---|---|---|
| Toronto Blue Jays | Sam White | 3B | West Virginia | Pulaski | 2023 |
| Los Angeles Angels | Ryland Zaborowski | 1B | Georgia | Pulaski | 2022 |
| Philadelphia Phillies | Jonathan Hogart | OF | Murray State | Greeneville | 2021 |
| Philadelphia Phillies | Bennett Markinson | C | Northwestern | Princeton | 2022 |
| Athletics | Jackson Holmes | RHP | Missouri State | Elizabethton | 2022 |
| Athletics | Owen Carapellotti | C | Georgetown | Elizabethton | 2022 |
| Minnesota Twins | Ian Daugherty | C | Oklahoma State | Greeneville | 2022 |
| New York Mets | John Bay | OF | Austin Peay | Pulaski | 2021 |
| Baltimore Orioles | Isaac Silva | RHP | Murray State | Burlington/Bluefield | 2023/24 |
| Boston Red Sox | Caleb Berry | C | Michigan State | Johnson City | 2023 |
| Los Angeles Angels | Aaron Graeber | OF | Delaware | Bristol | 2022 |
| Milwaukee Brewers | Tanner Perry | RHP | Illinois State | Johnson City | 2023 |
| Milwaukee Brewers | Michael Fowler | RHP | Southern Mississippi | Bristol | 2021 |
| Cincinnati Reds | Henry Hunter | C | Georgia | Kingsport | 2022 |
| Chicago White Sox | Trey Cooper | LHP | Liberty | Burlington | 2022/24 |
| Cleveland Guardians | Wes Burton | RHP | Tulane | Bristol | 2021 |
| Minnesota Twins | Carter Holjes | RHP | Florida Atlantic | Danville | 2021/24 |
| Baltimore Orioles | Zac Lampton | LHP | Florida International | Pulaski | 2022 |
| Baltimore Orioles | Marcos Reynoso | RHP | N/A | Pulaski | 2025 |
| Houston Astros | Brandon Nigh | 3B | Oakland | Bristol | 2022 |