In its first season as a collegiate wood-bat league, the Appalachian League had four players selected during the 2021 MLB Draft. An additional six signed as undrafted free agents (UDFAs). View UDFAs
2021 Drafted Players
| Round | Pick | Team | Player | Position | School | Appy League Team | Year |
|---|---|---|---|---|---|---|---|
| 14 | 432 | Los Angeles Dodgers | Jordan Leasure | RHP | University of Tampa | Elizabethton | 2021 |
| 17 | 503 | Washington Nationals | Brendan Collins | RHP | UNC Greensboro | Burlington | 2021 |
| 18 | 535 | Philadelphia Phillies | Malik Binns | RHP | Benedictine University (AZ) | Kingsport | 2021 |
| 19 | 582 | Los Angeles Dodgers | Gabe Emmett | RHP | Folsom Lake College (CA) | Burlington | 2021 |
2021 Undrafted Free Agents
| Team | Player | Position | School | Appy Team | Year |
|---|---|---|---|---|---|
| St. Louis Cardinals | Noah Mendlinger | OF | Georgia College & State | Bristol | 2021 |
| San Diego Padres | Brenden Heiss | RHP | Southeastern | Elizabethton | 2021 |
| Chicago White Sox | Everhett Hazelwood | RHP | Kansas | Danville | 2021 |
| Houston Astros | Ian Foggo | RHP | Lenoir-Rhyne | Johnson City | 2021 |
| Houston Astros | Jacob Coats | RHP | Houston Baptist | Princeton | 2021 |
| Tampa Bay Rays | Jack Snyder | RHP | Western Carolina | Danville | 2021 |