The Appalachian League had 14 players selected during the 2022 MLB Draft. An additional eight signed as undrafted free agents (UDFAs) or international free agents. View UDFAs
2022 Drafted Players
| Round | Pick | Team | Player | Position | School | Appy League Team | Year |
|---|---|---|---|---|---|---|---|
| 5 | 149 | New York Mets | D'Andre Smith | 2B | Southern California | Burlington | 2021 |
| 11 | 331 | Cleveland Guardians | Magnus Ellerts | RHP | Florida SouthWestern State College | Danville | 2021 |
| 11 | 339 | Boston Red Sox | Marques Johnson | RHP | Long Beach State | Johnson City | 2021 |
| 11 | 342 | Milwaukee Brewers | Cameron Wagoner | RHP | Eastern Michigan | Greeneville | 2021 |
| 12 | 352 | Miami Marlins | Cole Kirschsieper | LHP | Illinois | Kingsport | 2021 |
| 12 | 359 | New York Mets | Paul Gervase | RHP | Louisiana State | Bristol | 2021 |
| 13 | 380 | Pittsburgh Pirates | Miguel Fulgencio | LHP | Cowley CC (KS) | Johnson City | 2021 |
| 14 | 423 | Cincinnati Reds | Jared Lyons | RHP | George Mason | Danville | 2021 |
| 15 | 443 | Chicago Cubs | Haydn McGeary | C/1B | Colorado Mesa | Bluefield | 2022 |
| 15 | 460 | New York Yankees | Tayler Aguilar | OF | Grand Canyon | Greeneville | 2021 |
| 18 | 547 | St. Louis Cardinals | John Lynch | LHP | Xavier | Princeton | 2021 |
| 20 | 597 | Detroit Tigers (Did not sign) | Drew Conover | RHP | Seton Hall | Princeton | 2021 |
| 20 | 606 | Seattle Mariners | Nick Zona | 2B | James Madison | Pulaski | 2021 |
| 20 | 609 | Boston Red Sox | Connor Butler | LHP | Biola University (CA) | Burlington | 2021 |
2022 Undrafted Free Agents
| Team | Player | Position | School | Appy Team | Year |
|---|---|---|---|---|---|
| New York Yankees | Adam Stone | RHP | Harvard | Danville | 2021 |
| San Diego Padres | Zimo “Zack” Qin | LHP | MLB China Academy | Burlington | 2022 |
| Tampa Bay Rays | Joshuan Sandoval | 1B | MidAmerica Nazarene | Bluefield | 2021 |
| San Diego Padres | Braden Nett | RHP | St. Charles CC | Greeneville | 2021 |
| Washington Nationals | Caleb Farmer | C | Colorado Mesa | Burlington | 2021 |
| Arizona Diamondbacks | Caswell Smith | RHP | College of Charleston | Greeneville | 2022 |
| Toronto Blue Jays | Michael Brewer | RHP | ASA College Miami | Bristol | 2022 |
| San Francisco Giants | Dylan Cumming | RHP | Liberty | Burlington | 2022 |